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What are some severe complications and atypical manifestations of GERD?
GERD can Masquerade as Other Diseases
Chest Pain: Patients with GERD may have chest pain similar to angina or heart pain. Usually, they also have other symptoms like heartburn and acid regurgitation. If your doctor says your chest pain is not coming from the heart, don't forget the esophagus. On the other hand, if you have chest pain you should not assume it is your esophagus until you have been evaluated for a potential heart cause by your physician.
Asthma: Acid reflux may aggravate asthma. Recent studies suggest that the majority of asthmatics have acid reflux. Clues that GERD may be worsening your asthma include 1) asthma that appears for the first time during adulthood, 2) asthma that gets worse after meals, lying down or exercise, and 3) asthma that is mainly at night. Treatment of acid reflux may cure asthma in some patients and decrease the need for asthmatic medications in others.
Ear, Nose and Throat Problems: Acid reflux may be a cause of chronic cough, sore throat, laryngitis with hoarseness, frequent throat clearing, or growths on the vocal cords. If these problems do not get better with standard treatments, think about GERD.
Patients with Longstanding GERD Can Experience Severe Complications
Peptic Stricture: This results from chronic acid injury and scarring of the lower esophagus. Patients complain of food sticking in the lower esophagus. Heartburn symptoms may actually lessen as the esophageal opening narrows down preventing acid reflux. Stretching of the esophagus and proton pump inhibitor medication are needed to control and prevent peptic strictures.
Barrett's esophagus: The most serious complication of chronic GERD is Barrett's esophagus. Here the lining of the esophagus changes to resemble the intestine. Patients may complain of less heartburn with Barrett's esophagus-that's the good news. Unfortunately, this is a pre-cancerous condition: patients with Barrett's esophagus have approximately a 30-fold increased risk of developing esophageal cancer. These patients should be followed by endoscopy by a trained gastroenterologist familiar with this disease.
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American College of Gastroenterology P.O. Box 342260 Bethesda, MD 20827-2260 (301) 263-9000
©2006 American College of Gastroenterology